Modernize Testing​

We are working to end the FDA’s animal testing with the FDA Modernization Act of 2021 to eliminate the requirement that all new drugs go through extensive rounds of animal testing. Animal testing is outmoded because, unlike human biology-based test methods, animals are unreliable predictors of human response, delaying treatments and cures to patients and driving up drug costs. Revising FDA testing mandates will spare animals and save human lives.

The Issue

We are working to eliminate the requirement in the Federal Food, Drug and Cosmetics Act of 1938 for animal testing as the only test method for any new drug development protocol. The pharmaceutical industry is burdened by outdated FDA statutes and regulations that bar the use of faster, cheaper, and more reliable test methods.

There is urgency to address the problem because between 90 and 95 percent of drugs found safe in preclinical tests fail during human clinical trials due to toxicities not predicted by traditional animal tests or because of lack of efficacy. This exposes the public to unacceptable risk and stifles the movement of life-saving drugs into the marketplace.

The broader results are extraordinarily high costs for drugs, inordinately long wait periods bringing drugs to market, and, even after the drugs are approved for common use, the potential of serious side effects for consumers. However, significant investments in technology development and research have resulted in transformative breakthroughs in alternative methods, enabling us to leave most animal testing behind.

Recent Victory

With a bi-partisan vote of 392 to 28, the House passed the FDA Modernization Act as a rider to a larger package of FDA-related reforms, strengthening the chance of enactment this summer for a measure that would eliminate a statutory animal testing mandate for new drug development. The Senate Health, Education, Labor and Pensions Committee will soon hold a “markup” hearing on parallel legislation, which also includes the FDA Modernization Act as a rider.

While we still have work to do as the House and Senate work to reconcile differences in the two FDA legislative packages, we are on the path to see the adoption of a major national new policy to reduce animal testing and unleash the use of alternative test methods in our national efforts to test drugs formulated to cure or palliate disease.

Actions to Take

Our microsite has a wealth of information on animal testing

Tell your Senators

to support updates to outdated, unreliable FDA animal testing requirements for human drugs

Sign Our Petition

to tell FDA to update regulations for testing requirements!